Study A phase 1, open-label, single-dose, non-randomised study to evaluate pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients, Study contact information The Effects of inorganic nitrite on cardiac and skeletal muscle: Physiology, pharmacology, and therapeutic potential in patients with Chronic Heart Failure, Study contact information Dr VasileiosPanoulas. A multicenter, open-label, 8 day treatment study to assess the pharmacokinetics, safety and tolerability of fevipiprant delivered via a once daily chewable tablet in children aged 6 to <12 years with asthma. Aveir Dual-Chamber Leadless i2i IDE Study, Study contact information Name: Michelle RackhamEmail: M.Rackham@rbht.nhs.uk, Study Epidemiological trends and outcomes of hospital admissions for acute myocarditis and dilated cardiomyopathy in the National Health Service of England from 1998 onwards. Pulmonary hypertension in congenital heart disease, Study contact informationName: Dr Andrew ConstantineEmail: a.constantine@rbht.nhs.uk, Principal investigator Name:Alma IacobEmail:A.Iacob@rbht.nhs.uk, Principal investigator High density substrate evaluation and guided ablation therapy for atrial fibrillation: Heat-AF, Study contact informationName:Dr Haseeb ValliEmail:H.Valli@rbht.nhs.uk, Study Name:Helena SampaioEmail:m.fernandessampaio@rbht.nhs.uk, Study Name: Dr Carole RidgeEmail:C.Ridge@rbht.nhs.uk, Study Early Supported discharge with Pulmonary REhabilitation following Severe acute exacerbations of COPD Safety and Outcomes (ESPRESSO), Study Childhood Home Asthma Monitoring Project: prospective observational study to explore the use of contactless home monitoring devices and analysis to predict asthma risk, Study contact information A phase 2, double-blind, randomised, placebo-controlled, two-treatment, two-period crossover efficacy and safety study in Idiopathic Pulmonary Fibrosis (IPF)with Nalbuphine ER tablets for the treatment of cough. Nasal High-Flow Oxygen Therapy After Cardiac Surgery (NOTACS) Study: Effect of High-Flow Nasal Therapy on Patient-Centred Outcomes in Patients at High Risk of Postoperative Pulmonary Complications After Cardiac Surgery: A Multicentre Randomised Controlled Trial. Name: Joy PinguelEmail: A.Pinguel@rbht.nhs.uk, Study Study A randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of BG00011 in patients with Idiopathic Pulmonary Fibrosis. Dr Michael Loebinger, Study He also had the brilliant and revolutionary idea of integrating medical schools with hospitals, to ensure people would be treated effectively now and in future. Quantitive analysis of the 4-dimensional motion of the ascending aorta, Study contact information Managing abnormal glucose in cystic fibrosis (MAGIC)- the development of a self-management education programme for people with CFRD, Study contact information Name:Sarah CollinsEmail:s.collins@rbht.nhs.uk, Study Study contact information Stimulation of the left ventricular endocardium for Cardiac Resynchronisation Therapy in non-responders and previously untreatable patients, Study contact information Interstitial Lung Disease DNA Study, Study contact information Study Zephyrus II: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Pamrevlumab in Subjects with Idiopathic Pulmonary Fibrosis (IPF). Dr Samantha Irving, Study Name: Dr Koralia PaschalakiEmail:K.Paschalaki@rbht.nhs.uk, Study The Effects of Planned Intravenous Antibiotics on Activity and Sleep Quality in Cystic Fibrosis During the Post COVID-19 Lockdown Period, Study contact information Study contact information Study contact information Name: Pujan PatelEmail: p.patel@rbht.nhs.uk, Study Royal Brompton and Harefield hospitals are part of Guys and St Thomas NHS Foundation Trust. Study Study contact information Severe wheeze and asthma validation study, Study contact information MrAndreas Hoschtitzky. Name:Kevin KirbyEmail:K.Kirby@rbht.nhs.uk, Study A Randomized, Adaptive, Double-Blind, Placebo-Controlled, Parallel Arm, Phase 2b Study to Evaluate the Efficacy and Safety of Multiple Doses of BLU-5937 in Adult Participants With Refractory Chronic Cough, Study Name:Yvonne BinghamEmail:Y.Bingham@rbht.nhs.uk, Study Development of Cardiovascular Magnetic Resonance (CMR) sequences for future clinical use, Study contact information Name:Angela AramburoEmail:a.aramburocaragol@rbht.nhs.uk, Principal investigator An observational, retrospective multicentre medical record review to describe the post-authorisation early clinical experience of dupilumab in the treatment of adult severe asthma. Professor Martin Cowie, Study Find out more. Clinical Outcomes With Novel Modifier Therapy Combinations in CF, Study Study Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction (PiCSO-AMI-I), Study contact informationName: Paula RogersEmail:p.rogers@rbht.nhs.uk, Study UK lung volume reduction - multicentre observational, Study contact information Multicentre, open-label, active-controlled, randomised study to evaluate the efficacy and safety of an age and body weight-adjusted rivaroxaban regimen in children with acute venous thromboembolism, Study contact information A prospective pilot study: Magnetic Resonance Imaging (MRI) derived measures of bronchial arterial flow in the assessment and follow-up of patients with Cystic fibrosis (CF) who undergo bronchial artery embolisation. Study Name:Ashraf HussainEmail:A.Hussain@rbht.nhs.uk, Principal investigator Improving outcome measures for physiotherapy trials of airway clearance in adults with CF, Study contact information Name: Katherine SmithEmail: k.smith@rbht.nhs.uk, Study Assessing the utility of capillary sendaway NT-proBNP in pulmonary hypertension across the UK. Name:Dr Sandra ScottEmail: s.scott@rbht.nhs.uk. Assessment and validation of a device for measuring hydrogen peroxide in exhaled breath condensate in Healthy Volunteers, Study contact information Evaluating the nutritional impact of changing from 1% to 2% Propofol in a Cardiothoracic Adult Critical Care Unit, Study contact information Name:Ms Ana DoceHurtadoEmail:A.HurtadoDoce@rbht.nhs.uk, Principal investigator Measurement of novel indices of lung function in respiratory disease, Study contact information Which board certifications does Dr. Benjamin C. Tam have? Name: Yvonne BinghamEmail: y.bingham@rbht.nhs.uk, Study Study Pulmonary Hemodynamics during Exercise - Research Network. A randomized, double-blind, dose-ranging, placebo-controlled Phase 2a evaluation of the safety, tolerability and pharmacokinetics of PLN-74809 in participants with idiopathic pulmonary fibrosis (IPF). A RandomisEd ControlLed Study of PnEumRx Endobronchial Coil System Versus Standard-of-Care Medical MAnagement in the Treatment of Subjects with Severe Emphysema (ELEVATE) A Postmarket Surveillance Study (PMS). The gut microbiome in rheumatoid arthritis and bronchiectasis, Study contact information A 2x2 factorial randomised single blind open labelled trial to determine the clinical and cost -effectiveness of hypertonic saline (HTS 6%) and carbocysteine versus usual care over 12 months in non-cystic fibrosis bronchiectasis (BE): The Clear study, Study Study contact information Biomarker- guided intervention to prevent acute kidney injury after major non-cardiac surgery - the prospective multicenter randomized controlled interventional trial, Study contact informationName: Alessandra VerzelloniEmail: a.verzellonisef@rbht.nhs.uk. A phase iii randomized, double-blind, placebo-controlled trial to evaluate the efficacy and safety of prm-151 in patients with Idiopathic Pulmonary Fibrosis. Benjamin Garfield 1 , Charles McFadyen 2 , Charlotte Briar 2 , Caroline Bleakley 2 , Aikaterini Vlachou 2 , Melissa Baldwin 2 , Nick Lees 3 , Susanna . Name:Julia KellyEmail:J.Kelly@rbht.nhs.uk, Study Non-invasive detection of Pseudomonas aeruginosa lower airway infection in patients with Cystic Fibrosis, Study contact information Professor Eric Lim, Study Study contact informationName: Lyn PaulEmail: l.paul@rbht.nhs.uk, Study Validating digital mobility assessment using wearable technology The Mobilise-D Clinical Validation Study. Study Areas of Expertise. Phase III, Double-blind, Randomized, Placebo-Controlled, International Study to assess the Efficacy and Safety of Adjuvant Osimertinib versus Placebo in Patients with EGFR mutation-positive Stage IA2-IA3 Non-small Cell Lung Cancer, following Complete Tumoour removal. A cross sectional feasibility study examining the relationship between peak cough flow and respiratory function testing (spirometry) post bilateral sequential single lung transplantation, at a single centre cardiothoracic transplantation unit, Study contact information Study Name:Katherine RhatiganEmail:K.Rhatigan@rbht.nhs.uk, Study The London COPD cohort respiratory syncytial virus (RSV) study, Study contact information Name:Paolo ParediEmail:P.Paredi@rbht.nhs.uk. Name:Maria NunezEmail: M.Nunez@rbht.nhs.uk, Principal investigator Study contact information Professor Jadwiga Wedzicha, Study Fluctuation of airway function in children with asthma phenotype as a predictor of outcome, Study Study Name:Maria NunezEmail:M.Nunez@rbht.nhs.uk, Study Dr Vasileios Panoulas, Study A Study to Evaluate the Feasibility and Safety of the Millipede Transcatheter Annuloplasty Ring System in Patients with Functional Mitral Regurgitation, Study contact informationName: Debra DempsterEmail: D.Dempster@rbht.nhs.uk, Study NEURO-PACK: Neurologic prognosis after cardiac arrest in kids. Name: Alexis PerkinsEmail: a.perkins@rbht.nhs.uk, Study Name:Dr Rodney FranklinEmail:r.franklin@rbht.nhs.uk, Principal investigator Find Providers by Condition. Study contact information Identifying predictors for maintenance of exercise participation in children and young people with cystic fibrosis. Adherence to inhaled corticosteroids in young people with problematic severe asthma, Study contact information ROR-PH-303 - A StuDy EVAluatiNg the Long-Term EffiCacy and Safety of RalinEpag in Subjects with PAH via an Open-Label EXTENSION, Study Study Study contact information Study contact information Dr Christoph Nienaber, Study Name:Dr Anand DevarajEmail:a.devaraj@rbht.nhs.uk, Study Rhythm or rate control for CRT: the RHYTHMIC study, Study Name:Professor Piers DaubeneyEmail:P.Daubeney@rbht.nhs.uk, Principal investigator Study Professor Fan Chung, Study Study contact information Two part (double-blind inclisiran versus placebo [Year 1] followed by open-label inclisiran [Year 2]) randomized multicenter study to evaluate safety, tolerability, and efficacy of inclisiran in adolescents (12 to less than 18 years) with heterozygous familial hypercholesterolemia and elevated LDL-cholesterol (ORION-16), Study contact information Genetic determinants of Kawasaki disease for susceptibility and outcome, Study contact information Name:Olga ArchangelidiEmail:o.archangelidi@rbht.nhs.uk, Study A retrospective cohort study comparing the differences in baseline characteristics and outcomes in patients with influenza and COVID-19 treated with veno-venous extracorporeal membrane oxygenation (ECMO), Study contact information Study Dr. Benjamin C. Tam is certified by American Board of Orthopaedic Surgery. Clinical monitoring and biomarkers to stratify severity and predict outcomes in children with cystic fibrosis (CLIMB-CF). Dr. Benjamin Tam, MD, is an Orthopedic Surgery specialist practicing in Alhambra, CA with 31 years of experience. Mechanisms of increased susceptibility to rhinovirus infection in frequent and infrequent exacerbators of Chronic Obstructive Pulmonary Disease, Study contact information Name: Nicky MurrayEmail:N.Murray@rbht.nhs.uk, Study Name: Maria NunezEmail: m.nunez@rbht.nhs.uk, Study A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-445/TEZ/IVA Combination Therapy in Subjects With Cystic Fibrosis Who Are 6 Years of Age and Older, Study Name:Professor Susanna PriceEmail:S.Price@rbht.nhs.uk, Principal investigator Name:Dr Miles DalbyEmail:M.Dalby@rbht.nhs.uk, Study Study contact information Specialist centre for the treatment of heart and lung disease Royal Brompton and Harefield hospitals make up the largest specialist heart and lung centre in the UK and among the largest in Europe. Fibrotic Interstitial Lung Disease and nocturnal oxygen - An observational study of the effects of nocturnal hypoxaemia on patients with fibrotic interstitial lung disease, Study contact information A Pilot Study to exPlOre the exisTence and impact of FRAILTY in patients over the age of 70 undergoing cardiac interventions. Project Fizzyo: Remote monitoring and gaming technology for improving physiotherapy prescription, adherence and prediction of clinical outcomes in children with cystic fibrosis. Study Determining the clinimetric properties of structural and functional outputs of oxygen-enhanced magnetic resonance imaging in children and adults with cystic fibrosis (CF) and chronic suppurative lung disease (CSLD), Study contact information Ben Garfield's 8 research works with 180 citations and 459 reads, including: Single-center experience of temporary-permanent pacemaker use in COVID-19 patients supported with veno-venous ECMO: A . Name:Lisa JonesEmail:l.jones2@rbht.nhs.uk, Study 3 Adult Intensive Care Unit, Harefield Hospital, Harefield, UK. A study of concomitant epicardial left atrial appendage closure and catheter ablation in treating recurrent persistent atrial fibrillation after failed previous ablation, Study contact information A single arm pilot study of lung volume reduction in severe emphysema using bronchoscopic autologous blood instillation in combination with intra-bronchial valves, Study A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension, Study Hpitaux in Saint-Marcellin, Auvergne-Rhne-Alpes . Name: Mr Philip MolyneauxEmail: p.molyneaux@rbht.nhs.uk, Principal investigator Name: Anelise Catelan ZborowskiEmail: a.catelanzborowski@rbht.nhs.uk, Study Lung nodule Imaging Biobank for Radiomics and AI research (LIBRA), Study contact information Study contact informationName:Lyn PaulEmail:l.paul@rbht.nhs.uk. Name: Dr Chiara Bucciarelli-DucchiEmail: c.bucciarelli-ducci@rbht.nhs.uk, Principal investigator A single-centre, placebo-controlled, double-blinded, randomised, crossover study of Iloprost (Ventavis) in patients with Eisenmenger syndrome, Study contact information Study contact information Name:Paula RogersEmail: p.rogers@rbht.nhs.uk, Study Th2-low endotype biomarkers in exercise-induced asthma, Study contact information A drug utilization study (DUS) of alirocumab in Europe to assess the effectiveness of the dosing recommendation to avoid very low LDL-C levels. Court'ea CRDITS voiron . Name:Laura BarkerEmail: l.barker2@rbht.nhs.uk, Study ROR-PH-301 - A StuDy eVAluatiNg the EffiCacy and Safety of RalinEpag To Improve Treatment OUTCOMES in PAH Patients, Study contact informationName: Eleanor MorrisEmail: e.morris@rbht.nhs.uk, Study Study Dr DeepaArachchillage, Study Study contact information Study contact informationName: Dr Richard JonesEmail:r.jones@rbht.nhs.uk, Study Name: Peter JungEmail: p.jung@rbht.nhs.uk, Study We provide private heart and lung care services delivered by the. Study Reducer-I: An observational study of the Neovasc Reducer System, Study Name:Dr Benjamin GarfieldEmail:B.Garfield@rbht.nhs.uk, Study BG. Name:Professor Pallav ShahEmail:P.Shah@rbht.nhs.uk. The BRIDGE study- Bronchiectasis Research Involving Databases, Genomics and Endotyping to match the right treatment to the right patient, Study Study Sedation also poses a risk to patients with PH. Professor Susanna Price & Dr Vasileios Panoulas, Study Name:Aarif EifanEmail:A.Eifan@rbht.nhs.uk, Study Name:Dr Karthikan SrikanthanEmail:K.Srikanthan@rbht.nhs.uk, Study Outcome validation in noses of subjects with cystic fibrosis and non-CF volunteers, Study contact information Dr Julene Carvalho, Study Specialist services for lung disease Search LOCATIONS & DIRECTIONS We work from two main sites - Royal Brompton Hospital and Harefield Hospital. Improving Primary Ciliary Dyskinesia diagnosis using artificial intelligence, Study contact information INHALE: Personal pollution exposure and effects on the lungs in healthy and asthmatic individuals, Principal investigator Understanding susceptibility to fungal infection and evolution of antimicrobial resistance in chronic respiratory disease, Study contact information Study The role of conventional and advanced imaging modalities in formulating an optimal risk stratification strategy in patients with suspected cardiac sarcoidosis, Study contact informationName: Raheel AhmedEmail: r.ahmed2@rbht.nhs.uk, Study A Phase 3, Open-label, Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Tezacaftor in Combination With Ivacaftor in Subjects With Cystic Fibrosis Aged 6 Years and Older, Homozygous or Heterozygous for the F508del-CFTR Mutation. Name: David SmithEmail: d.smith22@rbht.nhs.uk, Study Study contact informationName:Paula RogersEmail:p.rogers@rbht.nhs.uk, Study Dr James Darius-Armstrong, Study Study contact informationName: Mathew VargheseEmail:M.Varghese@rbht.nhs.uk, Study Clustering and Phenotyping Interstitial Lung Disease, Study contact information Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: the COVID-HEART study, Study contact information Name: Professor John PepperEmail: j.pepper@rbht.nhs.uk, Study Name: Dr Joyce WongEmail: J.Wong@rbht.nhs.uk, Study Study contact information Name: Abigail WatsonEmail: a.watson2@rbht.nhs.uk. Professor Andrew Menzies-Gow, Study Study The MISTER trial is looking at testing whether minimal equipment pulmonary rehabilitation classes are as effective as those that use specialist equipment in terms of the effect on fitness levels, breathlessness and quality of life in the short and medium term. Inherited Cardiac cONditions In Kids Understanding the Genetics and Outcomes of Paediatric Inherited Cardiac Conditions, Study contact information The process of disclosure of the risk of cancer recurrence in patients following potentially curative lung cancer surgery: a multiple case study, Study contact information
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